Company Filing History:
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Years Active: 2013-2016
Title: Reiko Takasaka Lee: Innovator in Liver Function Quantification
Introduction
Reiko Takasaka Lee is a prominent inventor based in Baltimore, MD (US). She has made significant contributions to the field of liver function quantification through her innovative patents. With a total of 3 patents, her work focuses on improving clinical outcomes for patients with liver diseases.
Latest Patents
One of her latest patents is a quantification method for remaining liver function and a novel liver receptor imaging agent. This invention provides a test indicator for quantifying remaining liver function, which is crucial for assessing liver failure outcomes in clinical settings. The method utilizes a liver receptor imaging agent that targets the liver, helping to determine the necessity of liver transplantation for patients suffering from liver failure or disease. The radioactivity uptake of the test indicator is negatively correlated with the extent of liver reserve, and the patent also discloses a cutoff value for liver transplantation.
Another significant patent involves liver-targeting agents and their synthesis. This invention presents novel liver targeting agents with a lysine-based nitrilotriacetic acid structure that acquires multivalency with saccharide groups. The agent is designed to bind with a galactosamine chain or lactose chain, utilizing only one amino acid, L-lysine, to provide trivalency. The invention also details methods for synthesizing these agents, including the conjugation of multiple glycosides in a single step.
Career Highlights
Reiko has worked with esteemed organizations such as the Institute of Nuclear Energy Research and the Johns Hopkins University. Her experience in these institutions has allowed her to develop groundbreaking technologies that enhance liver function assessment.
Collaborations
Throughout her career, Reiko has collaborated with notable colleagues, including Yuan-Chuan Lee and Mei-Hui Wang. These partnerships have contributed to her innovative research and development efforts.
Conclusion
Reiko Takasaka Lee's contributions to liver function quantification through her patents demonstrate her commitment to advancing medical technology. Her work not only enhances clinical practices but also improves patient outcomes in liver disease management.