Raymond L Page

Title: Raymond L Page: A Pioneer in Stem Cell Research

Introduction:

Raymond L Page, based in Southbridge, MA, is a highly accomplished inventor and researcher in the field of stem cell biology. With a total of three patents to his name, Page has made significant contributions to the field, specifically in the areas of stem cell differentiation and de-differentiation. His pioneering work has opened up new possibilities for tissue engineering, regenerative medicine, and clinical applications.

Patents and Inventions:

1. Differentiating ES cells using a tenascin: This patent describes innovative assays for screening various substances, such as growth factors, immunostimulatory molecules, and extracellular matrix components, for their ability to induce directed differentiation of pluripotent and multipotent stem cells. These assays facilitate the identification of factors that influence the differentiation of stem cells, thereby advancing our understanding of cellular development.

2. Use of basic fibroblast growth factor in the de-differentiation of animal connective tissue cells: In this patent, Page introduces de-differentiation protocols to generate progenitor cells from adult connective tissue, specifically human fibroblasts. By culturing differentiated cells with a specific amount of FGF2, he successfully de-differentiates them into a more primitive state. These de-differentiated cells can be further cultured, characterized, and utilized for experimentation, amplification, and various clinical applications, including tissue and cell-based therapies.

Professional Career:

Raymond L Page has gained valuable experience and expertise by working with renowned institutions and companies in the field. He has contributed significantly to the advancements made by Advanced Cell Technology, Inc. and Worcester Polytechnic Institute. These institutions are at the forefront of stem cell research and have provided Page with a stimulating research environment to explore his innovative ideas further.

Collaborators:

Throughout his career, Page has collaborated with several talented scientists. Notable among them are Tanja Dominko and Michael D West. With their collective knowledge and expertise, they have pushed the boundaries of stem cell research and made significant contributions to advancing the field.

Conclusion:

Raymond L Page is a distinguished researcher and inventor who has left an indelible mark on the field of stem cell biology. His patents related to stem cell differentiation and de-differentiation have paved the way for new possibilities in regenerative medicine and clinical applications. By exploring innovative assays and protocols, his work has significantly contributed to our understanding of stem cell behavior, leading to potential breakthroughs in tissue engineering and therapeutic applications that could revolutionize healthcare in the future.