Raymond Evers

Title: The Innovative Contributions of Raymond Evers

Introduction

Raymond Evers is a notable inventor based in East Brunswick, NJ (US). He has made significant contributions to the field of biochemistry, particularly in the study of transport proteins. His innovative work has led to the development of a patented method that enhances the understanding of multi-drug resistance associated proteins (MRPs).

Latest Patents

Raymond Evers holds a patent for a "Simple quantitative fluorescent assay method for determining the activity of transport proteins of interest." This invention relates to a straightforward quantitative fluorescent assay method designed to assess the activity of transport proteins, specifically MRPs. The method involves a well-sealed culture of polarized cells expressing the transport protein of interest, which are grown to confluency on a permeable support. The process includes contacting the cells with a cell-permeable non-fluorescent derivative of a fluorescent compound, such as calcein AM, in one compartment. After a designated incubation period, the fluorescence intensity detected in a sample taken from the opposite compartment indicates the activity of the transport protein expressed in the cells. Additionally, the invention encompasses methods for qualitatively and quantitatively determining inhibitors and activators of transport proteins, as well as assessing the localization of plasma membrane-bound transport proteins in polarized cells.

Career Highlights

Raymond Evers is associated with Solvo Biotechnology, a company that focuses on innovative solutions in the field of drug development and transport protein research. His work at Solvo Biotechnology has allowed him to contribute to advancements in understanding the mechanisms of drug resistance, which is crucial for developing effective therapies.

Collaborations

Raymond Evers has collaborated with László Homolya, a fellow researcher in the field. Their partnership has likely fostered innovative approaches to studying transport proteins and their implications in drug resistance.

Conclusion

Raymond Evers is a distinguished inventor whose work has significantly impacted the field of biochemistry, particularly in understanding transport proteins. His patented method provides valuable insights into the activity of MRPs, contributing to advancements in drug development and resistance research.