Raymond E Counsell

Title: Innovations by Raymond E. Counsell: Pioneering Blood-Pool Delivery Systems

Introduction

Raymond E. Counsell, based in Ann Arbor, Michigan, is an accomplished inventor with a remarkable portfolio of 20 patents. His work primarily focuses on the development of innovative imaging solutions, particularly in the medical field. His latest inventions underscore a significant advancement in diagnostic imaging technology, especially concerning lipophilic imaging agents.

Latest Patents

One of Counsell's most notable patents is the "Blood-pool carrier for lipophilic imaging agents." This groundbreaking invention consists of a surface-modified lipoprotein-like oil-in-water emulsion designed as a selective delivery vehicle for lipophilic imaging agents or their derivatives. Key features of this invention include its ability to:

- Remain in the bloodstream for several hours,

- Show minimal early hepatic sequestration,

- Be cleared from the blood within 24 hours.

The mean diameter of the oil phase in this emulsion is less than 150 nm, which effectively minimizes sequestration by the reticuloendothelial system. Additionally, the surface of the oil phase is modified with a polyethylene glycol-modified phospholipid, preventing normal interactions with hepatocyte receptor sites. This patent allows for the incorporation of both radioactive and stable synthetic or semi-synthetic polyhalogenated triglycerides, enhancing the efficacy of radiographic imaging techniques.

Career Highlights

Throughout his career, Counsell has contributed significantly to research and development, particularly during his tenure at the University of Michigan and the Board of Regents. His expertise and innovative spirit have led to advancements that bridge the gap between complex scientific challenges and practical medical applications. His 20 patents reflect his dedication to enhancing imaging technologies and improving patient outcomes through better diagnostics.

Collaborations

Counsell's work has often involved collaboration with esteemed colleagues, including Marc A. Longino and Jamey Paul Weichert. These partnerships have facilitated the sharing of ideas and expertise, driving forward the innovative work being accomplished in the realm of medical imaging.

Conclusion

Raymond E. Counsell stands as a prominent figure in the field of medical imaging innovation. His contributions, particularly regarding blood-pool carriers for lipophilic imaging agents, demonstrate a robust intersection between science and practical healthcare solutions. Through his inventions and collaborations, Counsell continues to impact the field of diagnostics significantly, paving the way for future advancements.