The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 18, 1990

Filed:

May. 30, 1989
Applicant:
Inventors:

Raymond E Counsell, Ann Arbor, MI (US);

Marc A Longino, Ann Arbor, MI (US);

Jamey P Weichert, Ann Arbor, MI (US);

Susan P Schwendner, Ann Arbor, MI (US);

Assignee:

The University of Michigan, Ann Arbor, MI (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C11C / ; A61K / ;
U.S. Cl.
CPC ...
424-5 ; 424-11 ; 252312 ;
Abstract

Novel iodinated arylaliphatic triglyceride analogs as radiologic agents are liver and hepatocyte site-specific. The triglyceride backbone structure is preferably 1,3-disubstituted or 1,2,3-trisubstituted with, in some embodiments, a 3-substituted-2,4,6-triiodophenyl aliphatic chain wherein the chain has a structure similar to naturally occuring fatty acids. In another embodiment, a monoiodophenyl aliphatic chain is utilized. Any position remaining on the triglyceride backbone is substituted with a saturated or unsaturated aliphatic hydrocarbon chain of the type found in naturally occurring fatty acids. The triglyceride analogs can be radioiodinated. In a preferred embodiment, a lipid emulsion is provided as the carrier vehicle.


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Counsell, Raymond. (1990). Polyiodinated triglyceride analogs as radiologic agents (U.S. Patent No. 4957729). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/4957729

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