Location History:
- Irvington, NY (US) (2010 - 2012)
- Fairfield, CT (US) (2019)
Company Filing History:
2 out of 1,697 
1 out of 2,489 
1 out of 832,961 Years Active: 2010-2019
Title: Rastislav Levicky: Innovator in Nucleic Acid Detection
Introduction
Rastislav Levicky is a prominent inventor based in Irvington, NY (US). He has made significant contributions to the field of nucleic acid detection, holding a total of 4 patents. His innovative approaches have advanced the methodologies used in molecular diagnostics.
Latest Patents
One of Levicky's latest patents is titled "Detection of unlabeled nucleic acids by changing solubility of surface-associating probes." This patent provides methods and devices for detecting unlabeled nucleic acids based on the change of solubility of hydrophobic probes upon hybridization with a polynucleotide. In this embodiment, the probes are morpholino probes, which have a fluorophore attached. These probes are immobilized on a substrate that features fluorescence quenching functionality.
Another notable patent is "Capacitive morpholino diagnostics for analysis of nucleic acids." This patent explores the use of Morpholinos, a class of uncharged DNA analogues, for surface-hybridization applications. Monolayers of Morpholino probes on gold supports are fabricated using methods similar to those employed with DNA. These probes are utilized to hybridize efficiently and sequence-specifically with target strands. The hybridization-induced changes in the interfacial charge organization are analyzed with electrochemical methods, revealing insights into the molecular mechanisms connecting surface hybridization state to interfacial capacitance.
Career Highlights
Levicky has worked with prestigious institutions such as New York University and Columbia University. His work has been instrumental in developing advanced techniques for nucleic acid analysis, contributing to the broader field of molecular biology and diagnostics.
Collaborations
Some of his notable coworkers include Kenneth Shepard and Napoleon Tercero. Their collaborative efforts have further enhanced the research and development of innovative diagnostic tools.
Conclusion
Rastislav Levicky's contributions to the field of nucleic acid detection through his patents and collaborations highlight his role as a key innovator. His work continues to influence advancements in molecular diagnostics and research methodologies.