The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 07, 2019
Filed:
Nov. 13, 2014
Applicant:
New York University, New York, NY (US);
Inventors:
Rastislav Levicky, Fairfield, CT (US);
Wanqiong Qiao, Brooklyn, NY (US);
Yatao Liu, Tustin, CA (US);
Assignee:
New York University, New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C12Q 1/6816 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6816 (2013.01); C12Q 1/6816 (2013.01); C12Q 2525/113 (2013.01); C12Q 2565/101 (2013.01); C12Q 2565/519 (2013.01);
Abstract
Provided are methods and devices for detection of unlabeled nucleic acids. The detection methods are based on change of solubility of hydrophobic probes upon hybridization with a polynucleotide. In one embodiment, the probes are morpholino probes, having a fluorophore attached thereto. The morpholino probes are immobilized on a substrate that has fluorescence quenching functionality.