Ranjan Sen

Title: Ranjan Sen: Innovator in Transcriptional Regulation

Introduction

Ranjan Sen is a distinguished inventor based in Cambridge, MA (US). He has made significant contributions to the field of molecular biology, particularly in the area of transcriptional regulation. With a total of 3 patents, his work has had a profound impact on our understanding of gene expression.

Latest Patents

Sen's latest patents focus on nuclear factors associated with transcriptional regulation. He describes constitutive and tissue-specific protein factors that bind to transcriptional regulatory elements of immunoglobulin (Ig) genes, including both promoters and enhancers. These factors were identified and isolated using an improved assay for protein-DNA binding. His research highlights the potential to isolate genes encoding factors that positively regulate transcription, which can be employed to enhance the transcription of Ig genes. Notably, his work includes the gene encoding NF-kB, IkB, and their respective uses.

Career Highlights

Throughout his career, Ranjan Sen has worked with prestigious institutions such as the Massachusetts Institute of Technology and Harvard College. His innovative research has contributed to advancements in molecular biology and genetics.

Collaborations

Sen has collaborated with notable scientists, including David Baltimore and Phillip A. Sharp. These collaborations have further enriched his research and expanded the impact of his work in the scientific community.

Conclusion

Ranjan Sen's contributions to the field of transcriptional regulation exemplify the importance of innovation in scientific research. His patents and collaborations reflect a commitment to advancing our understanding of gene expression and its implications for biology.