Ramachandra N Rao

Title: The Innovations of Ramachandra N Rao

Introduction

Ramachandra N Rao is a notable inventor based in Indianapolis, IN (US). She has made significant contributions to the field of biotechnology, particularly in the area of polyketide synthesis and cell cycle regulation. With a total of four patents to her name, her work has had a considerable impact on scientific research and development.

Latest Patents

Among her latest patents is the invention of the Platenolide synthase gene, which is a DNA molecule isolated from Streptomyces ambofaciens. This gene encodes multi-functional proteins that direct the synthesis of the polyketide platenolide. Another significant patent involves the development of novel fusion proteins comprising cell cycle regulatory proteins. This invention provides fusion proteins that include human cyclin D1 and human CDK4, which are essential for understanding cell cycle regulation. The fusion proteins are designed with modifications that facilitate their purification, including the addition of histidine residues for immobilized metal affinity chromatography and antigenic determinants for monoclonal antibody-based purification.

Career Highlights

Ramachandra N Rao is currently employed at Eli Lilly and Company, where she continues to innovate and contribute to the field of biotechnology. Her work at Eli Lilly has allowed her to collaborate with leading scientists and researchers in the industry.

Collaborations

Some of her notable coworkers include Robert F Santerre and Stanley Gene Burgett. Their collaborative efforts have further advanced the research and development of biotechnological innovations.

Conclusion

Ramachandra N Rao's contributions to biotechnology through her patents and collaborations highlight her role as a significant inventor in her field. Her work continues to influence research and development in innovative ways.