Ralph L Henry

Title: Ralph L. Henry: Innovator in Protein Purification and Controlled Release Technologies

Introduction

Ralph L. Henry is a notable inventor based in Little Rock, AR (US), recognized for his contributions to the fields of protein purification and controlled release technologies. With a total of 12 patents to his name, he has made significant advancements that address challenges in these areas.

Latest Patents

Among his latest patents is the "Heparin affinity tag and application thereof." This invention describes affinity tags for recombinant protein purification that can mitigate or overcome disadvantages of prior affinity tag systems. The tags allow for efficient elution of desired recombinant proteins using simplified solution systems, such as alkali metal salt solutions. The affinity tag comprises an amino acid sequence that includes a repeating amino acid unit of BXXXBXX, where B represents an amino acid selected from histidine, lysine, and arginine, while X represents other amino acids.

Another significant patent is related to "Methods and compositions for X-ray induced release from pH sensitive liposomes." This invention includes compositions with pH sensitive lipid vesicles that release an agent after exposure to ionizing radiation. The methods described allow for controlled release of the agent, with the timing and location of release being managed through localized exposure to ionizing radiation.

Career Highlights

Ralph L. Henry has had a distinguished career, working at prominent institutions such as the University of Arkansas and the University of Pittsburgh. His work has focused on developing innovative solutions that enhance the efficiency of protein purification and drug delivery systems.

Collaborations

Throughout his career, Ralph has collaborated with esteemed colleagues, including Ellen M. Brune and Robert R. Beitle, Jr. These collaborations have contributed to the advancement of his research and the successful development of his patented technologies.

Conclusion

Ralph L. Henry's innovative work in protein purification and controlled release technologies has made a significant impact in the field. His contributions continue to influence research and development in these critical areas.