The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 05, 2019
Filed:
Dec. 19, 2017
The Board of Trustees of the University of Arkansas, Little Rock, AR (US);
Daniel Fologea, Boise, ID (US);
Ralph Henry, Fayetteville, AR (US);
Greg Salamo, Fayetteville, AR (US);
Yuriy Mazur, Fayetteville, AR (US);
Michael J. Borrelli, Little Rock, AR (US);
The Board of Trustees of the University of Arkansas, Little Rock, AR (US);
BioVentures, LLC, Little Rock, AR (US);
Abstract
Compositions including pH sensitive lipid vesicles comprised of a lipid layer, an agent, and an organic halogen such that the agent is released from the vesicles after exposure to ionizing radiation. Methods of delivering the agent to a target in a subject using the compositions provided herein are also described. The methods allow for controlled release of the agent. The timing of release of the agent from the lipid vesicle may be controlled as well as the location of release by timing and localizing the exposure to ionizing radiation exposure.