Ralph Casale

This inventor holds 11 USPTO granted patents and 3 published patent applications, plus 2 CIPO patents and 3 EPO patents. Top assignees: Ischemix, LLC, Qlaris Bio, Inc., Mayo Foundation for Medical Education and Research. Active years: 2011-2026.

IDiyas Innovation Intelligence. (2026). Inventor Profile: Ralph Casale. Retrieved from https://idiyas.com/inventor/ralph-casale

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

USPTO Granted Patents = 11 (Patent Applications = 3)

% Patents Active = 100.0

CIPO Patents = 2 (Patent Applications = 2)

EPO Patents = 3 (Patent Applications = 5)

Average Co-Inventor Count = 5.2

ph-index = 4

Forward Citations = 25(Granted Patents)

Company Filing History:

Mayo Foundation for Medical Education and Research

patents

4. 1 out of 1

Mayo Foundtation for Medical Education and Research

patent

where one patent can have more than one assignee

Years Active: 2011-2026

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11 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 12751939 - Topical ocular delivery of cromakalim (2026-10-06),

2. 12564573 - Topical ocular delivery of cromakalim (2026-03-03),

3. 12564572 - Topical ocular delivery of cromakalim (2026-03-03),

4. 11213509 - Compositions and methods for treating traumatic brain injury (2022-01-04),

5. 10744115 - Compositions and methods for treating traumatic brain injury (2020-08-18),

6. 9540417 - Compositions and methods for treating ischemia and ischemia-reperfusion injury (2017-01-10),

7. 9359325 - Lipoyl compounds and methods for treating ischemic injury (2016-06-07),

8. 8815937 - Lipoyl compounds and their use for treating ischemic injury (2014-08-26),

9. 8772250 - Compositions and methods for treating ischemia and ischemia-reperfusion injury (2014-07-08),

10. 8772249 - Compositions and methods for treating ischemia and ischemia-reperfusion injury (2014-07-08),

11. 7928067 - Compositions and methods for treating ischemia and ischemia-reperfusion injury (2011-04-19),

Title: Ralph Casale: Innovator in Traumatic Brain Injury Treatment

Introduction

Ralph Casale is a notable inventor based in Westford, MA (US), recognized for his contributions to the field of neuroprotective treatments. With a total of 11 patents, he has made significant strides in developing methods and compositions aimed at treating traumatic brain injuries (TBI).

Latest Patents

Among his latest patents, Casale has focused on compositions and methods for treating traumatic brain injury. His inventions relate to methods for preventing and treating neurodegenerative damage, particularly the secondary cascade of neurodegenerative damage that can occur after a TBI. These methods aim to improve functional outcomes associated with cognitive, behavioral, and sensorimotor functions. The inventions also include compositions for treating and preventing TBI, as well as compounds for use in the manufacture of medicaments designed to address secondary brain damage caused by TBI.

Career Highlights

Ralph Casale is currently associated with Ischemix, LLC, where he continues to innovate in the medical field. His work is pivotal in advancing treatments that can significantly enhance the quality of life for individuals affected by traumatic brain injuries.

Collaborations

Casale has collaborated with notable colleagues, including Alexander Baguisi and Reinier Beeuwkes, contributing to a dynamic environment of innovation and research.

Conclusion

Ralph Casale's work in the field of traumatic brain injury treatment exemplifies the impact of innovative thinking in medicine. His patents and ongoing research hold promise for improving outcomes for those affected by such injuries.

Profile summary based on public USPTO records.