The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 03, 2026

Filed:

Oct. 04, 2024
Applicants:

Qlaris Bio, Inc., Dedham, MA (US);

Mayo Foundation for Medical Education and Research, Rochester, MN (US);

Inventors:

Thurein M. Htoo, Westwood, MA (US);

Michael P. Fautsch, Rochester, MN (US);

Gary Allred, Wake Forest, NC (US);

Ralph Casale, Westford, MA (US);

Barbara M. Wirostko, Park City, UT (US);

Assignees:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4025 (2006.01); A61K 9/00 (2006.01); A61K 47/10 (2017.01); A61K 47/14 (2017.01); A61K 47/26 (2006.01); A61K 47/32 (2006.01); A61K 47/44 (2017.01); A61P 27/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4025 (2013.01); A61K 9/0048 (2013.01); A61K 47/10 (2013.01); A61K 47/14 (2013.01); A61K 47/26 (2013.01); A61K 47/32 (2013.01); A61K 47/44 (2013.01); A61P 27/06 (2018.01);
Abstract

An aqueous clear topical ocular solution of levcromakalim, or a pharmaceutically acceptable salt thereof, is provided in an effective therapeutic amount to treat the anterior portion of the human eye without the use of a covalent prodrug approach, a polymeric delivery system or a high level of toxic components, and with at least 4 months of shelf life stability, through the use of specifically discovered combinations of excipient components.


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