Raja G Achari

Title: **Innovative Contributions of Raja G Achari in Pharmaceutical Chemistry**

Introduction

Raja G Achari, an accomplished inventor based in Millington, NJ, has made significant strides in the field of pharmaceutical chemistry. With a total of five patents to her name, Achari's work focuses primarily on enhancing the release properties of antihistamine compounds, thereby improving their efficacy in medicinal applications.

Latest Patents

Among her recent innovations, Achari's most notable inventions include patents that revolve around the formation of diphenhydramine tannate and dexchlorpheniramine tannate. The **Hot melt method for preparing diphenhydramine tannate** involves a meticulous reaction process where diphenhydramine free base is combined with tannic acid at temperatures ranging from 75 to 150 degrees Celsius. This method ultimately yields a compound that exhibits extended release properties, making it a valuable addition to pharmaceutical compositions aimed at treating allergies in humans.

Similarly, her patent titled **Method for preparing dexchlor tannate** outlines a process for synthesizing dexchlorpheniramine tannate. This method requires the reaction of dexchlorpheniramine free base with tannic acid under the same temperature conditions. The final product produced also benefits from extended release characteristics, positioning it as a reliable antihistamine for patients.

Career Highlights

Raja G Achari has demonstrated her expertise through her associations with notable companies in the pharmaceutical industry, including Nastech Pharmaceutical Company, Inc. and Jame Fine Chemicals, Inc. Her experience in these organizations has played a pivotal role in shaping her innovations and has allowed her to contribute meaningfully to advancements in antihistamine formulations.

Collaborations

Throughout her career, Achari has worked alongside talented colleagues, including Charanjit R Behl and Jorge C deMeireles. These collaborations have enriched her research experience and propelled her contributions to the field, showcasing the importance of teamwork in driving scientific advancements.

Conclusion

Raja G Achari's innovative work, particularly in the realm of antihistamine compositions, has made a lasting impact on pharmaceutical chemistry. Her patented methods for preparing extended release formulations not only enhance the effectiveness of existing medications but also pave the way for future advancements in allergy treatment. The combination of her professional experience and collaborative spirit highlights the vital role of inventors like Achari in the ongoing pursuit of innovation in healthcare.