The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 06, 2005
Filed:
Aug. 14, 2003
Sham N. Redkar, Bound Brook, NJ (US);
Raja G. Achari, Millington, NJ (US);
Angelo R. Mellozzi, North Plainfield, NJ (US);
Vilas M. Chopdekar, Edison, NJ (US);
Sham N. Redkar, Bound Brook, NJ (US);
Raja G. Achari, Millington, NJ (US);
Angelo R. Mellozzi, North Plainfield, NJ (US);
Vilas M. Chopdekar, Edison, NJ (US);
Jame Fine Chemicals, Inc., Bound Brook, NJ (US);
Abstract
The invention pertains to a method for preparing dexchlorpheniramine ('dexchlor') tannate by reacting dexchlorpheniramine free base at a temperature of about 75 to about 150° C. with tannic acid neat or as an aqueous slurry containing up to about 20 wt. % water. The dexchlorpheniramine free base may be obtained by reacting a commercially available dexchlorpheniramine salt such as dexchlorpheniramine maleate with a base such as aqueous sodium hydroxide. The resultant dexchlor tannate has extended release properties and is useful in pharmaceutical compositions as an antihistamine for human beings.