This inventor holds 1 USPTO granted patent and 2 published patent applications and 1 EPO patent. Active years: 2026.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Years Active: 2026
Title: Rafael León Martínez: Research on NRF2-Related Liver Disease
Introduction
Rafael León Martínez is an inventor associated with Madrid, Spain. His patent work concerns inhibitors of the NRF2–β-TrCP interaction and their potential use in treating diseases linked to chronic inflammation and oxidative stress.
Latest Patents
The supplied information lists one patent associated with Martínez: “Tetrahydro-spiroindoline-pyrrolopyrrole-triones inhibitors of the NRF2-β-TrCP interaction for use in the treatment of fatty liver disease.” The invention describes compounds of a general formula and their derivative salts as inhibitors of the NRF2–β-TrCP interaction. It focuses on their potential application to NRF2-related diseases, particularly fatty liver disease. The listed patent count is 1 patent.
Career Highlights
Martínez is associated with Universidad Autónoma de Madrid and Fundación de Investigación Biomédica del Hospital Universitario de La Princesa. The supplied information does not specify his roles or dates of work at these institutions.
Collaborations
The listed coworkers associated with Martínez are Manuela García López and Antonio Cuadrado Pastor. The patent’s subject matter reflects research into molecular pathways relevant to inflammation, oxidative stress, and liver disease.
Conclusion
Rafael León Martínez’s listed invention explores NRF2–β-TrCP interaction inhibitors as a potential approach to treating fatty liver disease and other conditions associated with chronic inflammation and oxidative stress.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile