The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 31, 2026

Filed:

Jan. 13, 2022
Applicants:

Universidad Autonoma DE Madrid, Madrid, ES;

Consejo Superior DE Investigaciones Cientificas, Madrid, ES;

Universidad Miguel Hernandez DE Elche, Alicante, ES;

Fundacion DE Investigacion Biomedica Del Hospital Universitario DE LA Princesa, Madrid, ES;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/20 (2006.01); A61P 1/16 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
C07D 487/20 (2013.01); A61P 1/16 (2018.01); G01N 33/5008 (2013.01);
Abstract

The present invention relates to NRF2-βTrCP interaction inhibitors with general formula I and its derivate salts for use in the treatment of NRF2-related diseases caused by chronic inflammation and oxidative stress. More specifically the present invention relates to NRF2-βTrCP interaction inhibitors with specific formula I and its derivate salts for treating diseases of the liver related with chronic inflammation and oxidative stress, such as fatty liver disease.


Find Patent Forward Citations

Cuadrado Pastor, Antonio. (2026). Tetrahydro-spiroindoline-pyrrolopyrrole-triones inhibitors of the nrf2-β-trcp interaction for use in the treatment of fatty liver disease (U.S. Patent No. 12590100). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12590100

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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