Rachel T Simin

Title: Rachel T Simin: Innovator in G-Protein Fusion Receptors

Introduction

Rachel T Simin is a prominent inventor based in Salt Lake City, UT (US). She has made significant contributions to the field of biotechnology, particularly in the development of G-protein fusion receptors. With a total of 4 patents to her name, her work has the potential to impact various medical applications.

Latest Patents

Among her latest patents is the invention of G-protein fusion receptors and constructs encoding the same. This invention features G-protein fusion receptors that comprise at least one domain from a CaR, an mGluR, and/or a GABAreceptor. These receptors are fused directly or through a linker to a guanine nucleotide-binding protein (G-protein). Additionally, she has developed chimeric GABARs that include domains from both GABARs and mGluR subtype 8 (mGluR8) and/or a CaR. Another notable patent involves a novel human metabotropic glutamate receptor (mGluR) protein, which has been identified, sequenced, and cloned. This receptor can be utilized to screen for compounds that modulate mGluR activity, offering potential applications in the diagnosis and treatment of neurological disorders.

Career Highlights

Rachel T Simin is currently associated with NPS Pharmaceuticals, Inc., where she continues to advance her research and innovations. Her work has garnered attention in the scientific community, contributing to the understanding of receptor mechanisms and their implications in health.

Collaborations

Some of her notable coworkers include Thomas M Stormann and Lance G Hammerland, who have collaborated with her on various projects, enhancing the scope and impact of their research.

Conclusion

Rachel T Simin is a trailblazer in the field of biotechnology, with her innovative patents paving the way for advancements in medical science. Her contributions to G-protein fusion receptors and metabotropic glutamate receptors highlight her role as a key inventor in this domain.