The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 28, 2007

Filed:

Oct. 03, 2000
Applicants:

Thomas M. Stormann, Salt Lake City, UT (US);

Lance G. Hammerland, Salt Lake City, UT (US);

Laura L. Storjohann, Salt Lake City, UT (US);

James G. Busby, Simi Valley, CA (US);

James E. Garrett, Salt Lake City, UT (US);

Rachel T. Simin, Durham, NC (US);

Inventors:

Thomas M. Stormann, Salt Lake City, UT (US);

Lance G. Hammerland, Salt Lake City, UT (US);

Laura L. Storjohann, Salt Lake City, UT (US);

James G. Busby, Simi Valley, CA (US);

James E. Garrett, Salt Lake City, UT (US);

Rachel T. Simin, Durham, NC (US);

Assignee:

NPS Pharmaceuticals, Inc., Salt Lake City, UT (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/00 (2006.01); C08H 1/00 (2006.01); C07H 21/04 (2006.01); C12P 21/06 (2006.01); C12N 1/20 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention features G-protein fusion receptors and chimeric GABAreceptors (GABARs), nucleic acid encoding such receptors, and the use of such receptors and nucleic acid. G-protein fusion receptors comprise at least one domain from a CaR, an mGluR, and/or a GABAreceptor fused directly or through a linker to a guanine nucleotide-binding protein (G-protein). Chimeric GABARs comprise at least one of a GABAR extracellular domain, a GABAR transmembrane domain, or a GABAR intracellular domain and one or more domains from a mGluR subtype 8 (mGluR8) and/or a CaR.


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