Rachel Allysa Stern

Title: Rachel Allysa Stern and Automated Organoid Analysis

Introduction

Rachel Allysa Stern is an inventor associated with Rougemont, North Carolina, and Cell Microsystems, Inc. Her patent work addresses automated imaging, identification, and isolation of organoids, three-dimensional cell cultures used in biological research.

Latest Patents

Stern is named on 1 patent: “Automated System for Imaging, Identification, and Isolation of Organoids.” The invention combines a microwell array designed for organoid culture with an instrument system that images, tracks, and analyzes organoids over time. Releasable cellrafts in the microwells allow selected organoids to be transferred intact to a collection plate for further study.

The patent describes applications including single-organoid imaging, clonal organoid generation, parent-organoid subcloning, and RNA extraction for gene-expression or transcriptomic analysis. Demonstrations using mouse hepatic and pancreatic organoids illustrate the system’s potential for research workflows.

Career Highlights

Stern’s listed invention focuses on making organoid research more automated and reproducible. By integrating culture, imaging, analysis, and intact sample transfer, the system is designed to support downstream experiments while preserving individual organoids.

Collaborations

Stern is associated with Cell Microsystems, Inc. Her listed coworker is Caleb Macrae Fleming. The patent’s described work brings together organoid culture methods, imaging, and automated sample handling.

Conclusion

Rachel Allysa Stern’s patent highlights an integrated approach to tracking and isolating organoids, supporting researchers who need intact, individually selected samples for further analysis.