Location History:
- Milwaukee, WI (US) (1998 - 2001)
- Schenectady, NY (US) (2020)
Company Filing History:
1 out of 15 
1 out of 135 
1 out of 832,912 Years Active: 1998-2020
Title: Innovations by R Scott Duthie in Genetic Sequencing
Introduction
R Scott Duthie is an accomplished inventor based in Milwaukee, WI, whose contributions to the field of genetics are noteworthy. With a total of two patents to his name, Duthie has focused on advancing techniques in HLA typing and stabilization of nucleoside triphosphates.
Latest Patents
Duthie's latest patents have significantly impacted genetic research. One of his notable inventions is a method for Class I sequence-based typing of HLA-A, -B, and -C alleles by direct DNA sequencing. This method enhances the process of typing or sequencing HLA alleles from tissue samples, where exons 2 and 3 of the alleles are amplified simultaneously in a locus-specific manner. Following amplification, the individual exons are sequenced and compared to an HLA allele database, allowing for precise typing of the sample being analyzed.
Additionally, his patent concerning a composition for the stabilization of labeled nucleoside triphosphates represents another critical contribution. This patent details a preparation comprising a labeled nucleotide with specific compounds, including citrate and EDTA, designed to maintain the stability of the nucleotide at concentrations of at least 5 mM, ensuring the efficacy of genetic experimentation.
Career Highlights
Throughout his career, R Scott Duthie has worked for reputable organizations, including Pharmacia Biotech Inc. His innovative approaches have played a crucial role in enhancing genetic analysis methodologies, contributing to advancements in medical research and diagnostics.
Collaborations
Duthie has collaborated with notable colleagues in his field, including William H Hildebrand and Mary Ellexson. These partnerships have been instrumental in driving forward the development of genetic sequencing technologies and methodologies.
Conclusion
R Scott Duthie's contributions to the fields of genetic sequencing and biotechnology continue to influence research and development in medicine. His patents not only showcase his innovative spirit but also highlight the significant advancements in genetic analysis that are possible due to his work.