Company Filing History:
Years Active: 2006-2007
Title: R Rex Denton: Innovator in Genetic Research
Introduction
R Rex Denton is a notable inventor based in Madison, Connecticut, who has made significant contributions to the field of genetic research. He holds two patents that focus on the detection and application of CDK5 genetic markers, which are crucial for understanding cognitive responses to treatments for Alzheimer's disease.
Latest Patents
Denton's latest patents include groundbreaking work on CDK5 genetic markers associated with galantamine response. This patent discloses haplotypes in the CDK5 gene that are linked to cognitive responses to galantamine treatment. The compositions and methods outlined in this patent have various clinical applications, including articles of manufacture that comprise galantamine or its derivatives, which are approved for treating patients with specific CDK5 haplotypes. Additionally, the patent details methods and kits for predicting an individual's response to galantamine based on their haplotype profile, as well as methods for treating Alzheimer's patients tailored to their haplotype profiles.
Another significant patent by Denton involves methods for obtaining and utilizing haplotype data. This includes computer programs and databases designed to analyze gene haplotype information. The methods described allow for the measurement of haplotype frequencies in the general population, correlations between an individual's haplotypes or genotypes and clinical outcomes, and predictions of clinical responses to treatments based on genetic information.
Career Highlights
Throughout his career, R Rex Denton has worked with prominent companies in the pharmaceutical and genetic research sectors. Notable among these are Genaissance Pharmaceuticals, Inc. and Pgxhealth, LLC. His work has significantly advanced the understanding of genetic markers and their implications for treatment responses.
Collaborations
Denton has collaborated with esteemed colleagues in his field, including Richard S Judson and Gualberto Ruaño. These collaborations have further enriched his research and contributed to the development of innovative solutions in genetic analysis.
Conclusion
R Rex Denton is a distinguished inventor whose work in genetic research has the potential to transform treatment approaches for Alzheimer's disease and other conditions. His patents reflect a commitment to advancing medical science through innovative genetic applications.