The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 31, 2007

Filed:

Dec. 07, 2004
Applicants:

Jeroen Aerssens, Nieuwrode, BE;

Maria Athanasiou, Derby, CT (US);

Carlos Brain, Somerville, MA (US);

Nadine Cohen, Warren, NJ (US);

Bradley Dain, Hamden, CT (US);

R. Rex Denton, Madison, CT (US);

Richard S. Judson, Guilford, CT (US);

Vural Ozdemir, Long Beach, CA (US);

Carol R. Reed, Bethany, CT (US);

Inventors:

Jeroen Aerssens, Nieuwrode, BE;

Maria Athanasiou, Derby, CT (US);

Carlos Brain, Somerville, MA (US);

Nadine Cohen, Warren, NJ (US);

Bradley Dain, Hamden, CT (US);

R. Rex Denton, Madison, CT (US);

Richard S. Judson, Guilford, CT (US);

Vural Ozdemir, Long Beach, CA (US);

Carol R. Reed, Bethany, CT (US);

Assignee:

PGxHealth LLC, New Haven, CT (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C12P 19/34 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Haplotypes in the CDK5 gene associated with cognitive response to galantamine treatment are disclosed. Compositions and methods for detecting and using these CDK5 haplotypes in a variety of clinical applications are disclosed. Such applications include articles of manufacture comprising galantamine or derivatives thereof that are approved for treating patients having one of these CDK5 haplotypes, methods and kits for predicting the response of an individual to galantamine based upon his/her haplotype profile, and methods for treating Alzheimer's patients based upon their haplotype profile.


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