Company Filing History:
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Years Active: 1992-2007
Title: R Michael Blaese: A Pioneer in Gene Therapy Innovations
Introduction
R Michael Blaese, based in Rockville, MD, is a prominent figure in the field of gene therapy, holding a remarkable portfolio of 9 patents. His innovative work primarily focuses on developing therapeutic strategies utilizing engineered human cells for treating various genetic disorders.
Latest Patents
Among his latest contributions to the field, Blaese has developed significant methodologies for gene therapy. One notable patent details the genetic engineering of primary human cells with DNA encoding a therapeutic agent, which can be expressed in vivo. Additionally, he has been instrumental in creating a method for providing therapeutic effects in human patients through the use of CD34+ cells obtained from cord blood. These engineered cells are designed using a retroviral vector to include nucleic acid sequences that encode specific therapeutic agents. This revolutionary method has been particularly effective in treating newborn infants suffering from ADA deficiency.
Career Highlights
Throughout his career, R Michael Blaese has worked with esteemed organizations, such as the United States of America, represented by the Department of Health and the Secretary of the Department of Health and Human Services. His contributions have not only advanced scientific understanding but also paved the way for new treatment protocols in gene therapy that significantly benefit patients.
Collaborations
Blaese has collaborated with notable colleagues in the field, including Steven A Rosenberg and Craig A Mullen. Their joint efforts have further strengthened the research and development of innovative gene therapy techniques, enhancing the potential for life-saving treatments.
Conclusion
R Michael Blaese's impactful advancements in gene therapy demonstrate his commitment to improving human health through innovation. His numerous patents reflect a blend of creativity and scientific rigor, positioning him as a leading inventor in the ever-evolving landscape of medical science.