The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 10, 2006

Filed:

Apr. 08, 1994
Applicants:

Donald B. Kohn, Tarzana, CA (US);

R. Michael Blaese, Rockville, MD (US);

Craig A. Mullen, Sugar Land, TX (US);

Robert C. Moen, Mountain View, CA (US);

Inventors:

Donald B. Kohn, Tarzana, CA (US);

R. Michael Blaese, Rockville, MD (US);

Craig A. Mullen, Sugar Land, TX (US);

Robert C. Moen, Mountain View, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C12N 15/63 (2006.01); C12N 15/74 (2006.01); C12N 15/00 (2006.01); C12N 5/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method of providing a therapeutic effect in a human patient which comprises administering to the patient CD34+ cells obtained from cord blood. The CD34+ cells have been engineered with at least one nucleic acid sequence encoding a therapeutic agent. Such CD34+ cells may be engineered by transducing the cells with a retroviral vector including the nucleic acid sequence encoding the therapeutic agent. This method has been applied in treating newborn infants suffering from ADA deficiency.


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