This inventor holds 9 USPTO granted patents. Top assignee: Beckman Research Institute, City of Hope. Active years: 1992-2012.
Location History:
- South Pasadena, CA (US) (1992)
- S. Pasadena, CA (US) (1998)
- Pasadena, CA (US) (1996 - 2012)
- Greenbrae, CA (US) (1997 - 2012)
Company Filing History:
Years Active: 1992-2012
Title: R Bruce Wallace: Innovator in RNA Detection and Amplification
Introduction
R Bruce Wallace is a prominent inventor based in Greenbrae, CA (US). He has made significant contributions to the field of molecular biology, particularly in the detection and amplification of RNA sequences. With a total of 9 patents to his name, Wallace's work has advanced the understanding and capabilities in viral RNA identification.
Latest Patents
Among his latest patents is a method for amplification and detection of RNA sequences. This innovative process allows for the identification of a viral RNA nucleotide sequence present in a sample of peripheral blood cells. It involves amplifying the RNA simultaneously with at least one other RNA nucleotide sequence from virus-infected cells in the sample. The amplification reaction products are then analyzed with probes that are homologous to the authentic RNA and the other RNA sequence, enabling the identification of one or both RNA nucleotide sequences.
Another notable patent is the ligation amplification of nucleic acid sequences. This method focuses on identifying point mutations through a template-dependent ligation procedure. It also describes a template-dependent ligase chain reaction procedure for the amplification and detection of nucleic acid sequences.
Career Highlights
R Bruce Wallace is associated with the City of Hope, a leading research and treatment center. His work there has been instrumental in pushing the boundaries of RNA research and its applications in medical diagnostics.
Collaborations
Wallace has collaborated with notable colleagues, including Luis A Ugozzoli and John A Zaia. These partnerships have fostered a collaborative environment that enhances innovation and research outcomes.
Conclusion
R Bruce Wallace's contributions to RNA detection and amplification have made a significant impact in the field of molecular biology. His innovative patents and collaborations continue to influence research and diagnostics in virology.