Qais Shabandri

Title: Qais Shabandri: Innovator in Recombinant Human Insulin Crystallization

Introduction

Qais Shabandri is a notable inventor based in Bengaluru, India. He has made significant contributions to the field of biochemistry, particularly in the crystallization of recombinant human insulin. His innovative methods have the potential to enhance the manufacturing processes of this essential medication.

Latest Patents

Qais Shabandri holds a patent for the "Preparative crystallization of recombinant human insulin." This invention discloses a method for crystallizing recombinant human insulin at both lab and manufacturing scales. The process involves the use of a mixture of zinc chloride and sodium chloride, along with a higher concentration of organic solvent (IPA-19 to 25 million). Additionally, the pH is adjusted to 5.0 at a rapid rate of ≤5 minutes. The method also includes procedures that reduce settling time and alter holding temperatures to facilitate consistent protein crystal formation between 15 μm-30 μm, thereby increasing the robustness of the process.

Career Highlights

Qais Shabandri is currently employed at Biocon Limited, a leading biopharmaceutical company. His work focuses on developing innovative solutions that improve the efficiency and effectiveness of insulin production. His expertise in crystallization techniques has positioned him as a valuable asset in the field of biopharmaceuticals.

Collaborations

Qais collaborates with talented coworkers, including Ankita Saikia and Sai Srikar Kandukuri. Together, they contribute to advancing research and development in the biopharmaceutical sector.

Conclusion

Qais Shabandri's contributions to the crystallization of recombinant human insulin exemplify the impact of innovation in the biopharmaceutical industry. His work not only enhances manufacturing processes but also plays a crucial role in improving patient care.