Pui-Yan Kwok

Title: Pui-Yan Kwok: Innovator in Genetic Research

Introduction

Pui-Yan Kwok is a prominent inventor based in San Francisco, CA, known for his significant contributions to genetic research. With a total of two patents to his name, he has made remarkable advancements in the field of polynucleotide barcoding and genetic haplotyping.

Latest Patents

Kwok's latest patents include a method for polynucleotide barcoding, which involves immobilizing an isolated, individual polynucleotide on a solid phase and stretching it. This method utilizes target-specific hybridization probes to label targets, allowing for the optical detection of an individual label of an unamplified probe at each labeled target. The order of these labels creates a barcode representation of the polynucleotide, effectively illustrating the targets and their relative positions. Additionally, he has developed improved methods for determining genetic haplotypes and DNA mapping. These methods encompass the creation of amplified ssDNA, allele determination, and a DNA barcoding strategy that relies on direct imaging of individual DNA molecules, as well as the localization of multiple sequence motifs or polymorphic sites on a single DNA molecule.

Career Highlights

Throughout his career, Pui-Yan Kwok has worked at esteemed institutions such as the University of Illinois and the University of California. His work has significantly impacted the understanding of genetic sequences and their applications in various fields.

Collaborations

Kwok has collaborated with notable colleagues, including Ming Xiao and Paul R Selvin, contributing to the advancement of genetic research through teamwork and shared expertise.

Conclusion

Pui-Yan Kwok's innovative work in genetic research, particularly in polynucleotide barcoding and haplotyping, showcases his dedication to advancing scientific knowledge. His contributions continue to influence the field and pave the way for future discoveries.