Pranav Parmjit Singh

Title: Pranav Parmjit Singh: Innovator in Fusion Event Identification

Introduction

Pranav Parmjit Singh is a notable inventor based in Mountain View, CA (US). He has made significant contributions to the field of molecular biology, particularly in the analysis of cell-free nucleic acids. His innovative work focuses on identifying fusion events, which are critical in understanding various genetic conditions.

Latest Patents

Pranav holds a patent titled "Alignment Free Filtering for Identifying Fusions." This patent involves analyzing cell-free nucleic acids obtained from test samples to identify possible fusion events. The process includes sequencing and processing these nucleic acids to generate fragments. These fragments are then decomposed into kmers, which can be analyzed either de novo or compared to known targeted nucleic acid sequences associated with fusion gene pairs of interest. By identifying kmers that may have originated from fusion events, Pranav's method consolidates these kmers to generate gene ranges that match sequences in the fragments. A candidate fusion event can be called when one or more gene ranges span across the fragment.

Career Highlights

Pranav is currently employed at Grail, Inc., where he continues to advance his research and development efforts. His work is instrumental in the field of cancer detection and personalized medicine. With a focus on innovative solutions, he has contributed to the company's mission of transforming cancer detection.

Collaborations

Pranav collaborates with talented individuals such as Xiao Yang and Hyunsung John Kim. Their combined expertise enhances the research and development efforts at Grail, Inc., fostering an environment of innovation and discovery.

Conclusion

Pranav Parmjit Singh is a pioneering inventor whose work in identifying fusion events through innovative methodologies is making a significant impact in molecular biology. His contributions are vital for advancing cancer detection and treatment strategies.