Pradeep S Jadhavar

Title: Pradeep S Jadhavar: Innovator in Kinase Inhibitors

Introduction

Pradeep S Jadhavar is a notable inventor based in Greater Noida, India. He has made significant contributions to the field of medicinal chemistry, particularly in the development of kinase inhibitors. With a total of 2 patents to his name, Jadhavar's work focuses on innovative compounds that address critical health conditions.

Latest Patents

Jadhavar's latest patents include groundbreaking research on heterocyclic compounds as kinase inhibitors. The first patent discusses compounds that are useful in treating conditions associated with Checkpoint kinase (CHK), specifically targeting CHK-1 enzymes. The invention reveals a compound of formula (IA) that exhibits inhibitory activity against CHK-1 enzymes. It also outlines methods for treating conditions linked to excessive CHK-1 activity, along with pharmaceutical compositions and synthesis methods.

The second patent focuses on Ectonucleotide pyrophosphatase-phosphodiesterase-1 (ENPP1) inhibitors. This invention presents compounds that are beneficial in treating conditions related to the dysfunction of the ENPP1 enzyme. It details a compound of formula (J) that shows inhibitory activity against ENPP1. Additionally, it provides methods for treating conditions associated with the over-expression of the ENPP1 gene, along with relevant pharmaceutical compositions and kits.

Career Highlights

Throughout his career, Pradeep S Jadhavar has worked with several prominent companies, including 1CBio, Inc. and Sperogenix Therapeutics Limited. His experience in these organizations has allowed him to refine his expertise in drug development and innovation.

Collaborations

Jadhavar has collaborated with notable professionals in his field, including Sreekanth A Ramachandran and Brahmam Pujala. These collaborations have contributed to the advancement of his research and the successful development of his patented compounds.

Conclusion

Pradeep S Jadhavar is a distinguished inventor whose work in kinase inhibitors has the potential to significantly impact medical treatments. His innovative patents reflect his commitment to addressing critical health challenges through scientific research and development.