The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 10, 2025

Filed:

Jun. 13, 2024
Applicant:

1cbio, Inc., Moraga, CA (US);

Inventors:

Brahmam Pujala, Greater Noida, IN;

Amantullah Ansari, Greater Noida, IN;

Shreya Sapra, Greater Noida, IN;

Pradeep S. Jadhavar, Greater Noida, IN;

Dhananjay Pendharkar, Noida, IN;

Sreekanth A. Ramachandran, Greater Noida, IN;

Uzma Saeed, Okhla, IN;

Abhinandan Danodia, Greater Noida, IN;

Farha Khan, Noida, IN;

Sagar Patni, Noida, IN;

Sanjeev Soni, Greater Noida, IN;

Ashu Gupta, Noida, IN;

Sarvajit Chakravarty, Edmond, OK (US);

Balaji Dashrath Sathe, Greater Noida, IN;

Assignee:

1cBio, Inc., Moraga, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/04 (2006.01); C07D 401/14 (2006.01); C07D 403/14 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 491/056 (2006.01); C07F 5/02 (2006.01); C07F 9/6558 (2006.01);
U.S. Cl.
CPC ...
C07F 5/025 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 403/14 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 491/056 (2013.01); C07F 9/65583 (2013.01);
Abstract

The present invention discloses compounds useful in treatment of conditions associated with dysfunction of ectonucleotide pyrophosphatase/phosphodiesterase-1 (ENPP1) enzyme. Specifically, the present invention discloses compound of formula (J) which exhibit inhibitory activity against ENPP1. Method of treating conditions associated with over-expression of ENPP1 gene with such compound is disclosed. Uses thereof, pharmaceutical composition, and kits are also disclosed.


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