Pradeep Kumar Gupta

Title: Pradeep Kumar Gupta: Innovator in Chemical Synthesis

Introduction

Pradeep Kumar Gupta is a notable inventor based in Gwalior, India. He has made significant contributions to the field of chemical synthesis, particularly in the preparation of complex compounds. With a total of 2 patents to his name, Gupta's work showcases his expertise and innovative approach to chemistry.

Latest Patents

Gupta's latest patents include a method for the preparation of fentanyl and a process for the preparation of n-heneicosane. The fentanyl preparation method involves several steps, including the reaction of 4-piperidone hydrochloride monohydrate with aniline in a reducing environment to produce 4-anilinopiperidine. This compound is then reacted with phenethyl halide under reflux conditions in a highly alkaline medium to yield 4-anilino-N-phenethylpiperidine. Finally, this compound is converted to fentanyl by reacting it with propionyl chloride in the presence of halogenated hydrocarbons, followed by isolation and purification through solvent extraction and crystallization from petroleum ether at a temperature ranging from 60-80°C. The process for the preparation of n-heneicosane involves reacting 2,4-alkaneanedione with 1-bromooctadecane in absolute ethanol using 18-crown-6 as a catalyst to produce 2-heneicosanone, which is then reduced using hydrazine hydrate and potassium hydroxide in ethylene glycol to obtain n-heneicosane.

Career Highlights

Throughout his career, Pradeep Kumar Gupta has worked with esteemed organizations such as the Defence Research & Development Organisation and the Director General of Defence Research and Development Organisation. His experience in these institutions has allowed him to contribute to various innovative projects and research initiatives.

Collaborations

Gupta has collaborated with notable colleagues, including Kumaran Ganesan and Ramesh Chandra Malhotra. These collaborations have further enriched his research and development efforts in the field of chemical synthesis.

Conclusion

Pradeep Kumar Gupta is a distinguished inventor whose work in chemical synthesis has led to significant advancements in the preparation of important compounds. His contributions continue to impact the field positively, showcasing the importance of innovation in science and technology.