Location History:
- Aarhus, DK (2003 - 2005)
- Aarhus, DE (2005)
- Aarhus N, DK (2005 - 2009)
Company Filing History:
6 out of 1,327 
1 out of 17 Years Active: 2003-2009
Title: **The Innovative Mind of Poul Nissen**
Introduction
Poul Nissen is a renowned inventor based in Aarhus N, Denmark. He has made significant contributions to the field of ribosome research, holding a total of six patents that reflect his groundbreaking work. His innovations have implications in molecular biology and the development of new therapeutic agents.
Latest Patents
Among his most notable patents are methods related to the determination and uses of the atomic structures of ribosomes and ribosomal subunits, along with their ligand complexes. This invention provides techniques for producing high-resolution crystals of ribosomes and their subunits, which can be utilized to determine their three-dimensional structures. The high-resolution x-ray diffraction patterns obtained can identify ligand binding sites and aid in molecular modeling of ligands that interact with these structures. Additionally, Nissen's inventions describe methods for identifying ribosome-related ligands and designing ligands with specific ribosome-binding properties. This advancement allows the development of ligands aimed at inhibiting the growth of target organisms.
Another of his significant patents focuses on modulators of ribosomal function. It encompasses methods for producing high-resolution crystals and understanding ribosomal subunits in conjunction with protein synthesis inhibitors. This work also highlights the potential for designing targeted ligands capable of inhibiting protein synthesis, showcasing Nissen's dedication to advancing biological and medicinal applications.
Career Highlights
Poul Nissen's career has seen him affiliated with prestigious institutions such as Yale University, where his research laid the groundwork for numerous innovations in the understanding of ribosomes. His work at Rib-X Pharmaceuticals, Inc. contributed significantly to the development of novel antibiotic agents targeting ribosomal function. His inventor journey showcases a commitment to pushing the boundaries of scientific knowledge and application.
Collaborations
Throughout his career, Nissen has collaborated with esteemed colleagues such as Thomas A. Steitz and Peter B. Moore. These collaborations have fostered an environment of innovation, leading to research that has had a lasting impact on molecular biology and therapeutic development.
Conclusion
Poul Nissen's contributions to ribosomal research and his impressive portfolio of patents demonstrate his status as a leading inventor in his field. His work continues to inspire advancements in biology and medicine, promising new pathways for the development of therapeutic agents. His legacy as an innovator stands as a testament to the power of scientific inquiry and collaboration.