Ipswich, MA, United States of America

Pierre O Esteve

USPTO Granted Patents = 4 

Average Co-Inventor Count = 4.1

ph-index = 1

Forward Citations = 1(Granted Patents)


Location History:

  • Beverly, MA (US) (2018)
  • Ipswich, MA (US) (2021 - 2023)

Company Filing History:


Years Active: 2018-2023

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4 patents (USPTO):Explore Patents

Title: Pierre O Esteve: Innovator in Chromatin Analysis

Introduction

Pierre O Esteve is a notable inventor based in Ipswich, MA (US). He has made significant contributions to the field of molecular biology, particularly in the analysis of chromatin and the detection of molecular targets on chromosomal DNA. With a total of 4 patents, Esteve's work has advanced our understanding of genetic material and its implications in diagnostics.

Latest Patents

One of his latest patents is titled "Analysis of chromatin using a nicking enzyme." This invention provides various compositions and methods for analyzing chromatin. The composition may include a mixture of a nicking enzyme, four dNTPs, at least one labeled dNTP, and optionally, a polymerase. The method involves obtaining a sample containing chromatin, reacting it with the composition to selectively label the open chromatin, and analyzing the labeled sample.

Another significant patent is "Compositions and methods for detecting molecular targets on chromosomal DNA." This patent offers compositions, methods, and kits for identifying the presence and location of a target in chromosomal DNA. It features a nicking endonuclease fused to a binding domain that can bind to a constant region of an antibody. This innovation allows for the direct binding to a target or via an antibody that recognizes the target, which may correspond to a phenotype or pathology in diagnostic applications.

Career Highlights

Pierre O Esteve is currently associated with New England Biolabs, Inc., where he continues to innovate in the field of molecular biology. His work has been instrumental in developing methods that enhance the analysis of chromatin and the detection of molecular targets, contributing to advancements in genetic research and diagnostics.

Collaborations

Esteve has collaborated with notable coworkers such as Sriharsa Pradhan and Chaithanya Ponnaluri. Their combined expertise has furthered the development of innovative solutions in the field.

Conclusion

Pierre O Esteve's contributions to the field of molecular biology through his patents and collaborations have significantly impacted the analysis of chromatin and the detection of molecular targets. His work continues to pave the way for advancements in genetic research and diagnostics.

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