This inventor holds 3 USPTO granted patents, plus 1 CIPO patent. Top assignee: Merck + Co., Inc.. Active years: 1993-2002.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 1993-2002
Title: The Innovations of Philip S. Paress
Introduction
Philip S. Paress is a notable inventor based in Maplewood, NJ (US). He has made significant contributions to the field of biotechnology, particularly in the study of glutamate-gated chloride channels. With a total of 3 patents to his name, his work has implications for the development of novel insecticides and parasiticides.
Latest Patents
One of his latest patents involves DNA molecules encoding Ctenocephalides felis glutamate-gated chloride channels. This invention focuses on the unique properties of GluCl channels, which have only been observed in invertebrate organisms. The patent highlights how modulators of this channel can interfere with neurotransmission, leading to paralysis and death in target organisms. The isolation of a cDNA clone from the cat flea (CfGluCl-1) is a significant advancement, as it allows for the robust expression of a L-glutamate-gated chloride current. This channel can be activated and potentiated by avermectins, making it an excellent target for discovering new insecticides and parasiticides.
Another patent by Paress involves DNA encoding glutamate-gated chloride channels. This invention describes the cloning and characterization of channels that can be selectively opened by either avermectin or glutamate. The recombinant protein produced from this DNA has been purified and is used to identify modulators of receptor activity. These receptor modulators have potential applications as ectoparasiticides, antiparasitic agents, and insecticides.
Career Highlights
Philip S. Paress is currently employed at Merck & Co., Inc., where he continues to innovate in the field of biotechnology. His work has been instrumental in advancing the understanding of glutamate-gated chloride channels and their applications in pest control.
Collaborations
Throughout his career, Paress has collaborated with notable colleagues, including Doris F. Cully and Keith M. Gewain. These collaborations have contributed to the success of his research and the development of his patents.
Conclusion
Philip S. Paress is a distinguished inventor whose work in biotechnology has led to significant advancements in the understanding of glutamate-gated chloride channels. His patents have the potential to revolutionize pest control methods, showcasing the importance of innovation in this field.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile