Company Filing History:
Years Active: 2007-2012
Title: Philip O'Keefe: Innovator in Pharmaceutical Chemistry
Introduction
Philip O'Keefe is a notable inventor based in Loughborough, GB. He has made significant contributions to the field of pharmaceutical chemistry, holding a total of 2 patents. His work focuses on chemical processes that are essential for the manufacture of various pharmaceutical compounds.
Latest Patents
O'Keefe's latest patents include innovative processes and formulations. One of his notable inventions is related to the crystalline forms of 4-(6-chloro-2,3-methylenedioxyanilino)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-tetrahydropyran-4-yloxyquinazoline. This invention pertains to chemical processes useful in the manufacture of this compound, which is the active entity within AZD0530. It also covers particular crystalline forms of the compound, such as a difumarate salt and a trihydrate, along with pharmaceutical compositions containing these forms. Another significant patent involves a process for preparing 4-(hydroxy)-[1,4']bipiperidinyl-1'-carboxylic acid tert-butyl ester. This process includes hydrogenating a mixture of 4-hydroxypiperidine and 1-tert-butoxycarbonyl-4-piperidone in a suitable solvent, using a catalyst and at an appropriate pressure.
Career Highlights
Philip O'Keefe is currently associated with AstraZeneca AB, a leading global biopharmaceutical company. His work at AstraZeneca has allowed him to contribute to the development of innovative pharmaceutical solutions that address various health challenges.
Collaborations
O'Keefe has collaborated with several professionals in his field, including Mark Purdie and James Gair Ford. These collaborations have enhanced his research and development efforts, leading to advancements in pharmaceutical chemistry.
Conclusion
Philip O'Keefe is a distinguished inventor whose work in pharmaceutical chemistry has led to significant innovations. His patents reflect his commitment to advancing the field and improving healthcare solutions.