Philip Achacoso

Title: Innovations in Receptor Tyrosine Kinase Detection by Philip Achacoso

Introduction

Philip Achacoso, an accomplished inventor based in Union City, California, has made significant contributions to the field of biochemical assays. With one patented innovation to his name, Achacoso has focused his efforts on the detection of phosphorylation in receptor tyrosine kinases (RTKs), which are critical for various cellular processes.

Latest Patents

Achacoso's patent is titled "Receptor Tyrosine Kinase Assays," which outlines methods for detecting the activation of RTKs through phosphorylation. The method utilizes cells with two specific fusion products: one that fuses an RTK to a small fragment of beta-galactosidase and another that fuses a phosphotyrosine binding peptide to the large fragment of beta-galactosidase. When combined, these fragments form an active enzyme, facilitating the detection of phosphorylation when a beta-galactosidase substrate is added, thus indicating the occurrence of this significant biochemical event.

Career Highlights

Achacoso works at DiscoverX Corporation, a company known for its advancements in drug discovery and development, particularly in the realm of biological assays. His innovative contributions in the area of receptor tyrosine kinases have emphasized the importance of precise detection methods in pharmacological research.

Collaborations

Throughout his career, Achacoso has collaborated with notable colleagues, including Wei Feng and William Raab. These partnerships have fostered an environment of innovation and have driven forward the research methodologies in which Achacoso specializes.

Conclusion

In summary, Philip Achacoso stands out as a key inventor in the field of receptor tyrosine kinase assays. His patent not only showcases his inventive spirit but also represents important advancements in biochemistry, offering valuable insights into cellular functions that may impact future therapeutic developments.