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For the Inventor, By the Inventor

Cedar Grove, NJ, United States of America

Peter J Daniels

USPTO Granted Patents = 19

Average Co-Inventor Count = 2.0

ph-index = 8

Forward Citations = 181(Granted Patents)


Company Filing History:

goldMedal18 out of 1,829 
 
Schering Corporation
 patents
silverMedal1 out of 28 
 
Schering-plough Corporation
 patents

Years Active: 1976-1982

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19 patents (USPTO):Explore Patents
1. 4348516 - Microbiological methylation of aminoglycosyl-aminoglycosides (1982-09-07),
2. 4284764 - Process for the preparation of 5-fluoro-5-deoxy and (1981-08-18),
3. 4283528 - 1-N-aminohydroxyacyl derivatives of gentamicin B (1981-08-11),
4. 4234685 - Microbiological methylation of aminoglycosyl-aminoglycosides (1980-11-18),
5. 4212859 - 2'-Hydroxy-2'-desamino-4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitols, (1980-07-15),
6. 4178453 - Process for the preparation of 2,5-dideoxystreptamine and of a novel (1979-12-11),
7. 4117221 - Aminoacyl derivatives of aminoglycoside antibiotics (1978-09-26),
8. 4092359 - Process for the preparation of 2,5-dideoxystreptamine and of a novel (1978-05-30),
9. 4062947 - Di-N-alkylaminoglycosides, methods for their manufacture and novel (1977-12-13),
10. 4053591 - 5-Deoxy-4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitols, methods for their (1977-10-11),
11. 4049498 - Methods for the preparation of semi-synthetic aminocyclitol (1977-09-20),
12. 4044123 - 6'-N-alkyl-4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitols, methods for (1977-08-23),
13. 4011390 - Semi-synthetic aminocyclitol aminoglycoside antibiotics and methods for (1977-03-08),
14. 4002742 - 1-N-alkyl-4,6-di-(aminoglycosyl)-1,3-diaminocyclitols, methods for their (1977-01-11),
15. 4002608 - 1-N-alkyl-aminoglycoside-XK-88 derivatives and methods for their (1977-01-11),

Title: Innovative Contributions of Peter J Daniels in Antibacterial Agents

Introduction

Peter J Daniels, based in Cedar Grove, NJ, has made significant contributions to the field of antibacterial agents through his innovative work. With a remarkable portfolio of 19 patents, his research focuses on microbiological processes and chemical synthesis that yield effective antibacterial compounds.

Latest Patents

Among his latest patents, Daniels developed a method for the microbiological methylation of aminoglycosyl-aminoglycosides. This innovative process utilizes the microorganisms Micromonospora inyoensis 1550F-1G and M. purpurea strain 1124 to convert established antibiotics such as tobramycin, kanamycin A, kanamycin B, and dibekacin into their respective 3'-N-methyl and 3'-N-methyl-4'-C-methyl derivatives. These derivatives have demonstrated significant antibacterial activity against both gram-positive and gram-negative bacteria. Additionally, he has devised a novel process for producing 5-fluoro-5-deoxy and 5-epi-fluoro-5-deoxy-4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitols, further contributing to the development of new antibacterial agents.

Career Highlights

Daniels has held prominent roles at leading pharmaceutical companies, including Schering Corporation and Schering-Plough Corporation. His work within these organizations has contributed to advancements in the field of antibiotics and significant improvements in antibacterial treatments.

Collaborations

Throughout his career, Peter J Daniels has collaborated with distinguished colleagues, including Tattanahalli L Nagabhushan and Gerald H Wagman. These partnerships have fostered innovative approaches to antibiotic development and have played a key role in the research community.

Conclusion

Peter J Daniels stands out as a notable inventor in the field of antibacterial research. His 19 patents and ongoing contributions highlight the impact of his work on public health and the development of more effective antibacterial agents. As he continues to innovate, his legacy will surely influence future advancements in medicinal chemistry and microbiological applications.

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