The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 07, 1982
Filed:
Jun. 12, 1980
Applicant:
Inventors:
Bong K Lee, East Brunswick, NJ (US);
Gerald H Wagman, East Brunswick, NJ (US);
Dinanath F Rane, Emerson, NJ (US);
Joseph A Marquez, Montclair, NJ (US);
Peter J Daniels, Cedar Grove, NJ (US);
Assignee:
Schering Corporation, Kenilworth, NJ (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07H / ;
U.S. Cl.
CPC ...
536 10 ; 424180 ; 435 80 ; 536 / ;
Abstract
The microorganisms Micromonospora inyoensis 1550F-1G and M. purpurea strain 1124 each microbiologically convert tobramycin, kanamycin A, kanamycin B and dibekacin to their respective 3'-N-methyl and 3'-N-methyl-4'-C-methyl derivatives. The derivatives exhibit significant activity against representative gram positive and gram negative bacteria and may also be converted to other derivatives which have significant antibacterial activity.