The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 13, 1977

Filed:

Jul. 19, 1976
Applicant:
Inventors:

John J Wright, Cedar Grove, NJ (US);

Peter J Daniels, Cedar Grove, NJ (US);

Alan K Mallams, West Orange, NJ (US);

Tattanahalli L Nagabhushan, Parsippany, NJ (US);

Assignee:

Schering Corporation, Kenilworth, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07H / ;
U.S. Cl.
CPC ...
424180 ; 536-4 ; 536 10 ; 536 17 ; 536 18 ;
Abstract

1,2'-di-N-4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitols and 1,6'-di-N-alkyl-4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitols and their acid addition salts are valuable as antibacterial agents. Also disclosed are 2'-N-alkyl-4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitol antibacterial agents which are also useful as intermediates in the preparation of the 1,2'-di-N-alkyl-4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitols. Preferred compounds of this invention include 1,2'-di-N-ethylsisomicin and 1,6'-di-N-ethylsisomicin.


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