Location History:
- Vanløse, DK (2007 - 2015)
- Vanlose, DK (1991 - 2024)
Company Filing History:
22 out of 24 
7 out of 9 
5 out of 5 Years Active: 1991-2025
Title: The Innovative Contributions of Per Holm in Pharmaceutical Science
Introduction
Per Holm, a notable inventor based in Vanlose, Denmark, has made significant strides in the field of pharmaceutical innovations, holding an impressive portfolio of 35 patents. His work primarily focuses on enhancing the treatment of transplant patients, showcasing his dedication to improving patient outcomes through innovative pharmaceutical formulations.
Latest Patents
Among Holm's recent contributions, one of the most significant is his patent for "Tacrolimus for improved treatment of transplant patients." This invention describes an extended-release oral dosage form that utilizes tacrolimus or a pharmaceutically active analogue for once-daily immunosuppressive treatment, particularly benefiting kidney and liver transplant patients. This formulation aims to release the active substance over an extended period, enhancing pharmacokinetic parameters, which include decreased peak concentrations and increased bioavailability compared to conventional immediate-release forms.
Additionally, he has developed a "Stabilized tacrolimus composition." This patent focuses on a stable pharmaceutical composition that includes a solid dispersion of tacrolimus in a vehicle with a stabilizing agent. This formulation maintains a pH below 7 after re-dispersion in water, effectively preventing the formation of major degradation products, specifically the 8-epitacrolimus, during storage.
Career Highlights
Per Holm has had a distinguished career with substantial contributions to pharmaceutical sciences. He worked at Veloxis Pharmaceuticals A/S and Veloxis Pharmaceuticals Inc., where his research and innovations have played a crucial role in advancing medical treatments for transplant patients. His patents reflect a commitment to not only innovation but also the practical application of scientific discoveries.
Collaborations
Throughout his career, Holm has collaborated with prominent professionals in the field, including Tomas Norling and Robert D. Gordon. These partnerships have facilitated a rich exchange of ideas and have fostered innovation, leading to the development of groundbreaking pharmaceutical compositions that improve patient care.
Conclusion
Per Holm's impressive catalogue of patents exemplifies his significant contributions to pharmacology and the treatment of transplant patients. His innovations reflect a deep understanding of patient needs and the complexities of drug formulation, positioning him as an influential figure in the advancement of modern medicine. With continued research and development, Holm's work is sure to leave a lasting impact on pharmaceutical science and patient outcomes.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.