The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 23, 2022
Filed:
Nov. 13, 2018
Applicant:
Veloxis Pharmaceuticals A/s, Copenhagen, DK;
Inventors:
Nikolaj Skak, Virum, DK;
Per Holm, Vanlose, DK;
Assignee:
VELOXIS PHARMACEUTICALS, INC., Cary, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/20 (2006.01); A61K 9/14 (2006.01); A61K 31/436 (2006.01);
U.S. Cl.
CPC ...
A61K 9/2013 (2013.01); A61K 9/145 (2013.01); A61K 9/2077 (2013.01); A61K 31/436 (2013.01); Y10S 514/885 (2013.01);
Abstract
The invention relates to a stable pharmaceutical composition comprising comprising a solid dispersion of tacrolimus in a vehicle further comprising a stabilizing agent capable of providing a pH below 7 in the composition, as measured after re-dispersion in water, and preventing or reducing the formation upon storage of major degradation products of tacrolimus, in particular the 8-epitacrolimus.