Peizhi Luo

Title: Peizhi Luo: Innovator in Antibody Development

Introduction

Peizhi Luo is a prominent inventor based in Sunnyvale, California, known for his significant contributions to the field of biotechnology. With a total of eight patents to his name, he has made remarkable advancements in the design and selection of humanized antibodies.

Latest Patents

One of his latest patents focuses on humanized antibodies against vascular endothelial growth factor (VEGF). This invention provides methods for designing and selecting antibodies with high affinity and specificity, both in silico and in vitro. The patent details the development of monoclonal antibodies that can effectively bind to human VEGF, inhibiting VEGF-induced proliferation of endothelial cells and angiogenesis. These antibodies have potential applications in diagnosing and treating diseases such as cancer, age-related macular degeneration (AMD), and diabetic retinopathy. Another notable patent involves the generation of chimeric heteromultimers, which allows for the specific assembly of monomeric polypeptides into diverse antigen-binding units. This technique is crucial for creating a genetically varied repertoire of binding units, along with providing methods and kits for their production.

Career Highlights

Peizhi Luo has worked with notable companies in the biotechnology sector, including Abmaxis, Inc. and Xencor, Inc. His work has significantly impacted the development of therapeutic antibodies and innovative biotechnological solutions.

Collaborations

Throughout his career, Peizhi has collaborated with talented individuals such as Pingyu Zhong and Caili Wang, contributing to the advancement of antibody research and development.

Conclusion

Peizhi Luo's innovative work in antibody development has paved the way for new therapeutic approaches in treating various diseases. His contributions continue to influence the biotechnology field significantly.