Company Filing History:
Years Active: 2006
Title: Innovations of Paulo De Assis Melo
Introduction
Paulo De Assis Melo is an accomplished inventor based in Niteroi, Brazil. He has made significant contributions to the field of pharmaceuticals, particularly in developing compounds with therapeutic properties. His work focuses on creating innovative solutions for medical challenges, especially in treating heart conditions.
Latest Patents
Paulo De Assis Melo holds a patent for a compound known as Thienylhydrazon, which exhibits digitalis-like properties. This invention is particularly noteworthy for its positive inotropic effects, which enhance the strength of heart muscle contractions. The compound is characterized by a specific formula, where R is selected from hydrogen, alkyl groups of 1 to 6 carbon atoms, unsubstituted phenyl, and substituted phenyl. Additionally, the invention includes a novel method for synthesizing 3,4-methylenedioxybenzoyl-2-thienylhydrazone, also known as LASSBio-294. This compound is beneficial for treating congestive heart failure and muscle fatigue, while lacking the toxic effects commonly associated with digitalis glycosides.
Career Highlights
Paulo De Assis Melo is affiliated with the University System of Maryland, where he continues to engage in research and development. His work has garnered attention for its potential impact on cardiac health and muscle function. With a focus on innovative pharmaceutical solutions, he has established himself as a key figure in his field.
Collaborations
Paulo has collaborated with notable colleagues, including Roberto Takashi Sudo and Edson X Albuquerque. These partnerships have contributed to the advancement of his research and the successful development of his patented compounds.
Conclusion
Paulo De Assis Melo's contributions to the field of pharmaceuticals highlight the importance of innovation in addressing medical challenges. His work on Thienylhydrazon and its applications in treating heart conditions exemplifies the potential of scientific research to improve health outcomes.