Company Filing History:
Years Active: 2021-2023
Title: The Innovative Contributions of Pauline S. Smidt
Introduction
Pauline S. Smidt is a notable inventor based in Seattle, WA, recognized for her significant contributions to the field of recombinant expression vectors. With a total of 5 patents, her work has advanced the understanding and application of genetic engineering techniques.
Latest Patents
Among her latest patents, Smidt has developed innovative recombinant expression vectors that include a control sequence for the recombinant expression of proteins of interest. These vectors combine a mCMV enhancer sequence with a rat EF-1alpha intron sequence, which is particularly useful for tetracycline-inducible expression. Additionally, some vectors contain a 5' PiggyBac ITR and a 3' PiggyBac ITR, promoting genomic integration into host cell chromosomes. Her patents also disclose methods for selecting stable production cell lines for manufacturing proteins of interest, as well as mammalian host cells that utilize these inventive recombinant expression vectors.
Career Highlights
Throughout her career, Pauline has worked with prominent companies such as Just-evotec Biologics, Inc. and Just-evotec Biologies, Inc. Her expertise in the field has led to significant advancements in the production of proteins, enhancing the capabilities of biotechnological applications.
Collaborations
Pauline has collaborated with esteemed colleagues, including Jeffrey T. McGrew and E-Ching Ong, contributing to a dynamic research environment that fosters innovation and discovery.
Conclusion
Pauline S. Smidt's contributions to the field of recombinant expression vectors exemplify her dedication to advancing biotechnology. Her innovative patents and collaborative efforts continue to influence the industry positively.