Location History:
- Castle Rock, CO (US) (1993)
- Canal Winchester, OH (US) (2006)
- San Diego, CA (US) (2002 - 2009)
Company Filing History:
5 out of 1,187 
2 out of 2,077 
3 out of 832,812 Years Active: 1993-2009
Title: The Innovative Journey of Paul R. Russell: A Leader in DNA Repair Technologies
Introduction: Paul R. Russell, a prominent inventor based in San Diego, CA, has made significant contributions to the field of genetics and molecular biology. With a remarkable portfolio of 8 patents, his work primarily focuses on mammalian cell cycle checkpoint genes and DNA repair mechanisms. His inventions have greatly influenced both research and therapeutic methods in the field.
Latest Patents: Among his notable inventions, Russell's latest patents include crucial advancements in understanding and utilizing Mus81 proteins. The first patent describes novel mammalian cell cycle checkpoint genes and DNA repair genes, including cDNA and genomic DNA. This invention aims to isolate nucleic acids corresponding to these genes, alongside proteins they encode, and methods for using them in cellular treatments. His second patent introduces isolated mammalian Mus81-Eme endonuclease complexes, comprising Mus81 and Eme protein portions. Furthermore, it outlines a method for identifying chemical compounds that modulate mammalian cellular responses to DNA damage by evaluating their effects on the Mus81-Eme1 endonuclease complex.
Career Highlights: Russell's illustrious career includes significant tenures at The Scripps Research Institute, where he has honed his skills and developed his groundbreaking patents. His work in understanding DNA repair mechanisms has paved the way for advancements in therapeutic interventions, making a lasting impact in molecular biology.
Collaborations: Throughout his career, Russell has collaborated with esteemed colleagues, including Michael N. Boddy and Clare H. McGowan. These partnerships have fostered an environment of innovation, facilitating the development of new methodologies and discoveries in the realm of DNA research.
Conclusion: Paul R. Russell exemplifies the essence of innovation in the scientific community through his extensive research and patent portfolio. His work not only enhances our understanding of cell cycle checkpoints and DNA repair but also offers promising avenues for developing therapeutic solutions. As a leader in his field, Russell continues to inspire future generations of inventors and researchers.