Wilmington, DE, United States of America

Paul M Simon

USPTO Granted Patents = 9 

Average Co-Inventor Count = 2.8

ph-index = 5

Forward Citations = 130(Granted Patents)


Company Filing History:


Years Active: 1995-2012

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9 patents (USPTO):Explore Patents

Title: The Innovative Journey of Paul M. Simon

Introduction

Paul M. Simon, an inventive mind located in Wilmington, DE, has made significant contributions to the field of biotechnology. With a total of nine patents to his name, Simon has focused his efforts on developing advanced materials and methods related to vaccines and immune responses, showcasing his expertise in the intersection of immunology and pharmaceutical sciences.

Latest Patents

Among his latest patents is the "Targeted immune conjugate comprising an antibody to glycophorin A and a M2e peptide." This invention discloses materials and methods intended for vaccines, including innovative methods for delivering immunogens to the reticuloendothelial system via non-circulating lymphoid cells. Another notable patent involves "Methods of using .alpha.Gal oligosaccharides as immune system targeting." This invention relates to strategies for attenuating xenograft rejection in humans and old world monkeys. It focuses on using oligosaccharides containing a Gal.alpha.1-3Gal motif to neutralize or remove anti-.alpha.Gal antibodies, as well as offering methods for site-directed activation of the complement cascade or host leukocytes. Such groundbreaking work has implications in the development of pharmaceutical compositions that effectively bind anti-.alpha.Gal antibodies in vivo or ex vivo.

Career Highlights

Throughout his career, Paul M. Simon has held significant roles at esteemed organizations such as Neose Technologies, Inc. and the DuPont Merck Pharmaceutical Company. His tenure at these companies reflects his dedication and impactful contributions to research and development in the biotechnology sector.

Collaborations

Simon has collaborated with notable professionals in his field, including coworkers David A. Zopf and Edward J. McGuire. Together, they have engaged in transformative research that has advanced their collective understanding of immunological applications and therapeutic measures.

Conclusion

Paul M. Simon's extensive patent portfolio and his work at leading companies position him as a key innovator in the biotechnology industry. His pioneering inventions not only advance the field of vaccine development but also offer new methods for addressing complex immune responses. As he continues to innovate, Simon's impact on modern medicine is likely to grow, resulting in new therapies and improved patient outcomes.

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