Paul Buske

Title: The Innovative Contributions of Paul Buske

Introduction

Paul Buske is a notable inventor based in Madison, WI (US), recognized for his significant contributions to the field of biotechnology. With a total of 3 patents to his name, he has made strides in developing treatments for various diseases through innovative oligonucleotide compositions.

Latest Patents

Among his latest patents, one focuses on the treatment of angiopoietin like 7 (ANGPTL7) related diseases. This patent provides oligonucleotide compositions that inhibit ANGPTL7 and reduce intraocular pressure when administered to an eye. The compositions include nucleoside modifications that enhance their effectiveness. Another significant patent addresses MST1 related diseases and disorders. This invention discloses compositions comprising an oligonucleotide that targets MST1, which may include a small interfering RNA (siRNA) or an antisense oligonucleotide (ASO). The methods outlined in this patent aim to treat conditions associated with MST1 variants by providing an oligonucleotide that targets MST1 to a subject.

Career Highlights

Paul Buske is currently associated with Empirico Inc., where he continues to push the boundaries of medical research and innovation. His work is pivotal in developing new therapeutic strategies that can significantly impact patient care.

Collaborations

Some of his notable coworkers include Omri Gottesman and Shannon Bruse, who collaborate with him on various projects within the company.

Conclusion

Paul Buske's innovative work in biotechnology, particularly in the development of oligonucleotide therapies, showcases his commitment to advancing medical science. His contributions are vital in addressing complex health challenges, and his patents reflect a promising future in treatment options.