The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 27, 2025

Filed:

Aug. 07, 2024
Applicant:

Empirico Inc., San Diego, CA (US);

Inventors:

Omri Gottesman, San Diego, CA (US);

Shannon Bruse, San Diego, CA (US);

Paul Buske, Madison, WI (US);

Brian Cajes, San Diego, CA (US);

David Jakubosky, San Diego, CA (US);

Sarah Kleinstein, San Diego, CA (US);

David Lewis, Madison, WI (US);

David Rozema, Cross Plains, WI (US);

John Vekich, San Diego, CA (US);

Assignee:

Empirico Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); A61P 11/00 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C12N 15/1136 (2013.01); A61P 11/00 (2018.01); C12N 2310/11 (2013.01); C12N 2310/14 (2013.01); C12N 2310/315 (2013.01); C12N 2310/321 (2013.01); C12N 2310/322 (2013.01); C12N 2310/351 (2013.01);
Abstract

Disclosed herein are compositions comprising an oligonucleotide that targets MST1. The oligonucleotide may include a small interfering RNA (siRNA) or an antisense oligonucleotide (ASO). Also provided herein are methods of treating conditions associated with MST1 variants that include providing an oligonucleotide that targets MST1 to a subject.


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