Company Filing History:
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Years Active: 2020-2023
Title: Paul Avan: Innovator in Hearing Loss Treatment
Introduction
Paul Avan is a notable inventor based in Clermont-Ferrand, France. He has made significant contributions to the field of auditory health, particularly in the prevention and treatment of hearing loss and impairment. With a total of 2 patents, his work focuses on innovative approaches to restore auditory functions.
Latest Patents
Avan's latest patents revolve around the use of gasdermin, specifically gasdermin A, B, C, D, DFNA5, and DFNB59 (or pejvakin). These inventions aim to modulate cellular redox homeostasis, with a particular emphasis on pejvakin as an antioxidant. Additionally, he has developed a virally-mediated gene therapy designed to restore genetically-impaired auditory and vestibular functions in individuals suffering from Usher syndrome. This gene therapy utilizes an AAV2/8 vector that expresses at least one USH1 gene product, preferably SANS.
Career Highlights
Throughout his career, Paul Avan has worked with prestigious institutions such as the Institut Pasteur and the Centre National de La Recherche Scientifique. His research has significantly advanced the understanding of hearing loss and has opened new avenues for treatment.
Collaborations
Avan has collaborated with esteemed colleagues, including Christine Petit and Sedigheh Delmaghani. These partnerships have further enriched his research and contributed to the development of innovative solutions in auditory health.
Conclusion
Paul Avan's contributions to the field of hearing loss treatment highlight his dedication to improving auditory health through innovative research and collaboration. His work continues to inspire advancements in the medical community.